Mass spectrometry is an essential technique for identifying and measuring molecules in complex samples. It is widely used to analyse proteins, peptides, metabolites and drug compounds, offering high sensitivity and specificity, particularly when combined with chromatographic techniques such as LC-MS and GC-MS. Yet before analysis even begins, the quality of the results depends on one critical step: sample preparation.
A mass spectrometer can only analyse what effective sample preparation has released. Insufficient homogenisation can limit extraction yield, purity and result reproducibility. Thanks to 3D bead-beating technology, Precellys homogenisers efficiently process complex matrices and deliver consistent, reproducible homogenisation. This helps release molecules of interest and optimise sample preparation before analysis.
To support laboratories in optimising their workflows, Bertin Life Sciences experts share their guidance on preparing samples for mass spectrometry, gaining greater control over homogenisation steps and achieving more reliable LC-MS and GC-MS results.
