Sample preparation homogenizers - Bertin Technologies

Sample preparation homogenizers

Sample preparation is critical to master molecules extraction from biological samples. Bertin Health & Life Sciences offers efficient and flexible Precellys tissue homogenizers for grinding any samples prior to analysis.

The preparation of samples for the homogenization of biological tissue and the extraction of molecules of interest is an often laborious and difficult operation that is nevertheless crucial for any analysis. Bertin Health & Life Sciences offers a high-performance range of tissue homogenizers under the Precellys® brand. Bertin Health & Life Sciences makes sample preparation quicker and more efficient.

Tissue homogenization for reproducible & efficient sample preparation

In order to extract the molecules of interest (extraction of RNA, DNA, proteins, metabolites, etc.) from biological samples, sample preparation procedures generally include a tissue homogenization or cell disruption step.
The Precellys® homogenizers from Bertin Health & Life Sciences use bead-beating technology to homogenize biological samples, such as human, animal or plant tissues, or to lyse micro-organisms. In this way, the biological samples are ground via multi-directional movement (3D bead-beating), the speed of which can reach up to 10,000 rotations per minute, depending on the equipment. Bead-beating is the gold standard method for tissue homogenization compared to standard techniques such as: mortar & pestle, sonication, blender, high pressure homogenizer. It takes just a few dozen seconds to homogenize the samples, which are then ready for an analysis of the molecules of interest (nucleic acids, proteins, metabolites) using different analysis techniques: PCR, sequencing, Western Blot, liquid chromatography, etc. This represents a considerable time saving that simplifies sample preparation protocols.

The high-performance characteristics of the Bertin Health & Life Sciences homogenizers, together with a wide variety of lysing and grinding kits, offer excellent reproducibility and a great degree of flexibility in a broad range of research areas including microbiology, pharmacology, cancer, forensic medicine, the environment, and even agronomy.

The Precellys® range, fully safe, versatile tissue homogenization

   The Precellys® range allows you to prepare samples in full safety and without cross contamination, for both routine applications and R&D projects.

• For infrequent use, the Minilys® homogenizer allows you to prepare up to three samples at the same time. Its flexibility (0.5, 2 and 7 ml tubes) and its small size make it ideal for laboratories needing conventional sample preparation.

• The Precellys® 24 homogenizer can accommodate up to 24 biological samples in 2 ml and 0.5 ml tubes simultaneously. This robust appliance has been designed for daily use in laboratories with biological safety level 3.

• For even greater versatility, the Precellys® Evolution can accommodate up to 96 samples at the same time with six different tube volumes (from 0.3 ml to 15 ml), and meets the safety standards of laboratories with biological safety level 3.Avoid degradation of your heat-sensitive samples during homogenization with Cryolys® Evolution, the sample cooling system compatible with Precellys®

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Protein extraction from food samples with Precellys Evolution

Genclis SAS is a CRO mainly working on food samples. In this application their aim is to extract proteins recognized by IgE antibodies from allergic patients. The challenge is to extract protein with the best possible quality. The Precellys Evolution extracts high quality proteins in large quantities from dry food samples. Moreover, the capacity to process six tubes of 15mL is a real advantage and saves time.


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