[PRECELLYS] MicroRNA expression profiling of individual rat hypothalamic nuclei - Bertin Technologies

[PRECELLYS] MicroRNA expression profiling of individual rat hypothalamic nuclei

Sources: Neuroendocrinologie Moléculaire de la Prise Alimentaire, University of Paris-Sud 11, UMR 8195, Orsay, France and Neuroendocrinologie Moléculaire de la PriseAlimentaire, CNRS, Centre de Neurosciences, Paris-Sud UMR8195, Orsay, France.


MicroRNAs (miRNAs) finely tune messenger RNA (mRNA) expression. As the brain is a highly heterogeneous tissue, physiologically relevant miRNA expression profiling greatly benefits from sampling brain regions or nuclei. MiRNA expression profiling from individual samples is also important for investigating potential differences between animals according to their physiological and pathophysiological status[1].


[1] L.Amar et al., MicroRNA expressionprofiling of hypothalamic arcuate andparaventricular nuclei from single rats using Illumina sequencing technology;Journal of Neuroscience Methods;http://dx.doi.org/10.1016/j.jneumeth.2012.05.033


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