Nucleic acid isolation is the starting point of most downstream experiments. It is an essential step in molecular biology. DNA and RNA extraction can be divided in two main steps: cell lysis and purification. As these molecules are fragile, especially for RNA, it is important to ensure efficient grinding while preserving biological compounds.
Thanks to the 3D bead-beating technology, the Precellys Evolution guarantees efficient grinding, homogenization, or lysis of any biological sample.
This Application Note compares the homogenization efficiency of the Precellys Evolution and the new Precellys Evolution Touch through DNA and RNA extractions from two different types of sample (heart and liver). It also highlights how nucleic acid extraction kits allow high yields of purified DNA and RNA.