[PRECELLYS] Metabolites and RNA extraction from fish liver

The goal of this study was to investigate both transcriptomic and metabolomic changes in response to xenoestrogen exposure. Male stickleback fish were used as a model organism for this study as they are environmentally relevant and the stickleback genome draft sequence was available. Key to this study was the ability to carry out both omics techniques upon the same liver tissue homogenate [1] [2].

[1] I. Katsiadaki et al., Aquatic Toxicologydoi:10.1016/j.aquatox.2009.07.005[2] H. Wu et al., Anal. Biochem. 37 (2008) 204–212